---
title: "NV-Generate-MR-Brain — 3D Brain MRI Synthesis"
description: "Generate synthetic brain MRI across T1w, T2w, FLAIR, and SWI contrasts with cross-sequence synthesis via ControlNet."
canonical: https://nvidia-medtech.github.io/models/nv-generate-mr-brain.html
audience: [engineer, researcher]
last_updated: 2026-06-10
source: models/nv-generate-mr-brain.html
---
# NV-Generate-MR-Brain

3D Brain MRI Synthesis

Commercial

Generate synthetic brain MRI across T1w, T2w, FLAIR, and SWI contrasts with cross-sequence synthesis via ControlNet.

MRI [HuggingFace](https://huggingface.co/nvidia/NV-Generate-MR-Brain) [GitHub](https://github.com/NVIDIA-Medtech/NV-Generate-CTMR) [Paper](https://arxiv.org/abs/2508.05772)

### Run it with an agent

Install the skill, then just ask your agent in plain language. `medagent.nv_generate_mr_brain`

install skill Copy

```bash
npx skills add NVIDIA-Medtech/medical-AI-skills --skill nv-generate-mr-brain
```

Try saying

“Generate a synthetic T1 brain MRI from /data/brain\_request.json using nv-generate-mr-brain.”

“Can this skill synthesize a skull-stripped FLAIR brain MRI?”

“Produce a FLAIR brain MRI sample using nv-generate-mr-brain and report the output geometry.”

[Skill on GitHub →](https://github.com/NVIDIA-Medtech/medical-AI-skills/tree/dev/skills/nv-generate-mr-brain) [How agent skills work](https://agentskills.io)

### Finetune it with an agent

Install the skill, then just ask your agent in plain language. `medagent.nv_generate_mr_brain_finetune`

install skill Copy

```bash
npx skills add NVIDIA-Medtech/medical-AI-skills --skill nv-generate-mr-brain-finetune
```

Try saying

“Fine-tune the NV-Generate MR brain diffusion model using images listed in /data/mrbrain/datalist.json.”

“Check whether my MR-brain finetune datalist is runnable before launching the GPU job.”

“Validate my MONAI-style datalist and stage the configs for an MR-brain finetune, but don't launch training yet.”

[Skill on GitHub →](https://github.com/NVIDIA-Medtech/medical-AI-skills/tree/dev/skills/nv-generate-mr-brain-finetune) [How agent skills work](https://agentskills.io)

Engineering & research use only — not a medical device, not for diagnosis or clinical decision-making. Skills follow the open [Agent Skills spec](https://agentskills.io).